Tools and practical guidance to support HIV indicator condition-guided testing

OptTEST (Optimising testing and linkage to care for HIV across Europe)
www.opttest.eu

An EU Commission-funded project which aims to help reduce the number of undiagnosed people with HIV infection in Europe and to promote timely treatment and care. Its website contains a series of tools to support HIV indicator condition-guided testing, including a slide set, an online training module for staff offering testing, a practical tool about how set up HIV indicator-guided testing in a clinic and a list of further resources.

HIV for non-HIV specialists Diagnosing the undiagnosed. A practical guide for healthcare professionals in secondary care to support improved detection and diagnosis of HIV in Europe (2016) First edition by Dr Rachel Baggaley. Second edition by Dr Ann Sullivan, Dr Emma Devitt & Ruth Lowbury. Adapted for the European context by Dr Miriam Taegtmeyer. MEDFASH and JUSTRI.

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Guidance and guidelines

HIV Indicator Conditions: Guidance for Implementing HIV Testing in Adults in Health Care Settings

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Gökengin D, Geretti AM, Begovac J et al (2014) 2014 European Guideline on HIV testing. Int J STD AIDS 25: 695-704.

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World Health Organization (2015) Consolidated guidelines on HIV testing services.

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European Centre for Disease Prevention and Control (2010) HIV testing: increasing uptake and
effectiveness in the European Union
. Stockholm.

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Epidemiology of HIV in Europe

European Centre for Disease Prevention and Control/WHO Regional Office for Europe. HIV/AIDS surveillance in Europe 2015. Stockholm: ECDC; 2016

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European Centre for Disease Prevention and Control. Thematic report: Continuum of HIV care.
Monitoring implementation of the Dublin Declaration on Partnership to Fight HIV/AIDS in Europe and Central Asia: 2017 progress report. Stockholm: ECDC; 2017

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European Centre for Disease Prevention and Control. The status of the HIV response in the European Union/European Economic Area, 2016. Stockholm. ECDC: 2017.

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References

1. Uthayakumar S, Nandwani R, Drinkwater T et al (1997) The prevalence of skin disease in HIV infection and its relationship to the degree of immunosuppression. Br J Dermatol. 137:595-8. http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2133.1997.tb03793.x/abstract

2. Uthayakumar S, Nandwani R, Drinkwater T et al (1997) The prevalence of skin disease in HIV infection and its relationship to the degree of immunosuppression. Br J Dermatol. 137:595-8. http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2133.1997.tb03793.x/abstract

3. European Centre for Disease Prevention and Control/WHO Regional Office for Europe. HIV/AIDS surveillance in Europe 2015. Stockholm: ECDC; 2016. http://ecdc.europa.eu/en/publications/_layouts/forms/Publication_DispForm.aspx?List=4f55ad51-4aed-4d32-b960-af70113dbb90&ID=1607

4. World Health Organization Regional Office for Europe (2016) Action Plan for the health sector response to HIV in the European Region. Copenhagen: WHO Regional Office for Europe, 2016. http://www.euro.who.int/en/health-topics/communicable-diseases/hivaids/publications/2016/action-plan-for-the-health-sector-response-to-hiv-in-the-who-european-region.-draft-5.4-2016

5. European Centre for Disease Prevention and Control. Thematic report: Continuum of HIV care.
Monitoring implementation of the Dublin Declaration on Partnership to Fight HIV/AIDS in Europe and Central Asia: 2017 progress report
. Stockholm: ECDC; 2017. https://ecdc.europa.eu/en/publications-data/thematic-report-continuum-hiv-care

6. Marks G, Crepaz N, Janssen RS (2006) Estimating sexual transmission of HIV from persons aware and unaware that they are infected with the virus in the USA. AIDS. 20(10):1447-50. http://journals.lww.com/aidsonline/fulltext/2006/06260/Estimating_sexual_transmission_of_HIV_from_persons.12.aspx

7. Trickey A, May MT, Vehreschild J-J et al (2017) Survival of HIV-positive patients starting antiretroviral therapy between 1996 and 2013; a collaborative analysis of cohort studies. Lancet HIV. 4(8):e349-e356. http://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(17)30066-8/fulltext

8. Mocroft A, Lundgren JD, Sabin ML et al (2013) Risk factors and outcomes for late presentation for HIV-positive persons in Europe: results from the Collaboration of Observational HIV Epidemiological Research Europe Study (COHERE). PLoS Med. 10:e1001510. http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1001510

9. Rodger AJ, Cambiano V, Bruun T et al (2016) Sexual activity without condoms and risk of HIV transmission in serodifferent couples when the HIV-positive partner is using suppressive antiretroviral therapy. JAMA.316(2):171-181. http://jamanetwork.com/journals/jama/fullarticle/2533066

10. European Centre for Disease Prevention and Control/WHO Regional Office for Europe. HIV/AIDS surveillance in Europe 2015. Stockholm: ECDC; 2016. http://ecdc.europa.eu/en/publications/_layouts/forms/Publication_DispForm.aspx?List=4f55ad51-4aed-4d32-b960-af70113dbb90&ID=1607

11. Pharris A, Quinten C, Noori T et al (2016) Estimating HIV incidence and number of undiagnosed individuals living with HIV in the European Union/European Economic Area, 2015. Euro Surveill. Euro Surveill. 21(48): 30417. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388115/

12. Sullivan AK, Curtis H, Sabin CA et al. (2005) Newly diagnosed HIV infections: review in UK and Ireland. BMJ. 330:1301-2. www.ncbi.nlm.nih.gov/pmc/articles/PMC558202

13. Champenois K, Cousien A, Cuzin L et al (2013) Missed opportunities for HIV testing in newly-HIV-diagnosed patients, a cross sectional study. BMC Infect Dis. 13:200. https://bmcinfectdis.biomedcentral.com/articles/10.1186/1471-2334-13-20

14. HIV in Europe secretariat (2012) HIV Indicator Conditions: Guidance for Implementing HIV Testing in Adults in Health Care Settings. http://newsite.hiveurope.eu/Finalised-Projects/Guidance-HIV-Indicator-Conditions (New edition in development)

15. Sullivan AK, Raben D, Reekie J et al (2013) Feasibility and effectiveness of indicator condition-guided testing for HIV: results from HIDES I (HIV indicator diseases across Europe study). PLoS One. 8:e52845. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0052845

16. Raben D. Mocroft A, Rayment M et al (2015) Auditing HIV Testing Rates across Europe: Results from the HIDES 2 Study. PLoS One. 10(11):e0140845. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140845

17. Uthayakumar S, Nandwani R, Drinkwater T et al (1997) The prevalence of skin disease in HIV infection and its relationship to the degree of immunosuppression. Br J Dermatol. 137:595-8. http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2133.1997.tb03793.x/abstract

18. Sullivan AK, Raben D, Reekie J et al (2013) Feasibility and effectiveness of indicator condition-guided testing for HIV: results from HIDES I (HIV indicator diseases across Europe study). PLoS One. 8:e52845. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0052845

19. Hsu DT, Ruf M, O’Shea S et al (2013) Diagnosing HIV infection in patients presenting with glandular fever-like illness in primary care: are we missing primary HIV infection? HIV Med. 14:60-3. http://onlinelibrary.wiley.com/doi/10.1111/j.1468-1293.2012.01023.x/pdf

20. Sullivan AK, Raben D, Reekie J et al (2013) Feasibility and effectiveness of indicator condition-guided testing for HIV: results from HIDES I (HIV indicator diseases across Europe study). PLoS One. 8:e52845. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0052845

21. Gökengin D, Geretti AM, Begovac J et al (2014) 2014 European Guideline on HIV testing. Int J STD AIDS 25: 695-704. http://std.sagepub.com/content/25/10/695.full.pdf+html

22. Sullivan AK, Raben D, Reekie J et al (2013) Feasibility and effectiveness of indicator condition-guided testing for HIV: results from HIDES I (HIV indicator diseases across Europe study). PLoS One. 8:e52845. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0052845

23. Sullivan AK, Raben D, Reekie J et al (2013) Feasibility and effectiveness of indicator condition-guided testing for HIV: results from HIDES I (HIV indicator diseases across Europe study). PLoS One. 8:e52845. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0052845